INTER- AND INTRA-SPECIES CONVERSION EFFICACIES OF NORWEGIAN PRION ISOLATES ESTIMATED BY SERIAL PROTEIN MISFOLDING CYCLIC AMPLIFICATION

Inter- and intra-species conversion efficacies of Norwegian prion isolates estimated by serial protein misfolding cyclic amplification

Abstract Prion diseases, including chronic wasting disease (CWD) in cervids, are fatal neurodegenerative disorders caused by the misfolding of cellular prion proteins.CWD is known to spread among captive and free-ranging deer in North America.In 2016, an outbreak of contagious CWD was detected among wild reindeer in Norway, marking the first occurr

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Appendiceal Neoplasms: Diagnosis, Management and Follow-up

Appendicectomy is one of the most performed surgical procedures.Neoplasms of the appendix are identified in approximately 1% of appendiceal specimens, and the incidence seems to be rising.The aim of this review was to summarize the current data on these neoplasms, focusing on the recent classification, clinical manifestations, management, and follo

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